Shedding: common for A SCAM-2000 but not for Jynneos

A minor clarification for Amazing Polly

The lesion on your upper arm from the smallpox vaccine A SCAM-2000 can last up to 6 weeks. It must be covered as live virus grows in the lesion and frequently spread to spouses and children of soldiers receiving it. If they are immune compromised they can get generalized vaccinia, which can be life-threatening. There is a hyperimmune serum available to save life-threatening cases.

Jynneos is different. It is supposed to be non-replicating. Allegedly it doesn’t shed. I guess we will find out whether it can shed, when it is used in the US.

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